0674 CPAP Adherence and Response to Cognitive Processing Therapy for PTSD in Veterans with Obstructive Sleep Apnea

Abstract Introduction Cognitive processing therapy (CPT) is a recommended first-line psychotherapy treatment for veterans with PTSD. Veterans PTSD are at higher risk sleep disorders including obstructive apnea (OSA), and there evidence that OSA can exacerbate vice versa. Several studies have shown CPAP use associated improvement in symptoms. CPT an effective, yet time resource intensive option, making it critical to identify potential health factors impacting its efficacy. This retrospective chart analysis of diagnosed evaluated the effect adherence on response CPT. Methods Medical records patients seen VA Health Care System were reviewed received between 1-12 sessions documented weekly Checklist DSM-5 (PCL-5) scores, Patient Questionnaire-9 (PHQ-9) issued machine OSA. Data collected included demographics, (mean use, % days greater than 4 hrs./night mean residual hypopnea index, mask leak), symptoms (PCL-5 PHQ-9 scores). For each outcome, we estimated linear mixed-effects model; models PCL-5 allowed heterogeneous variances veteran. Results study identified 25 receiving access The median age was 43 years, BMI 35.6, AHI 2.4. Patients duration 11.0 weeks. There significant scores over course (both p < .001). least ≥70% did not significantly impact during Residual leak Conclusion While nonadherence appears be contributing factor reduced effectiveness evidence-based treatments PTSD, our revealed regardless adherence. Given nature small sample size this study, further research needed expand these findings. Support (If Any)